Candice Cassia Poon, MD, PhD, FRCSC

MD obtained at the University of Alberta

PhD obtained at the University of Calgary in Neuro-Oncology and Neuroimmunology under the supervision of Dr. V. Wee Yong

FRCSC obtained after a Neurosurgical Residency at the University of Calgary

Clinical and Research Fellowship in Neurosurgical-Oncology at the University of Texas MD Anderson Texas Center (Research supervisors were Dr. Padmanee Sharma and Dr. Frederick Lang)

Dr. Candice C. Poon

Areas of Research

Neuro-Oncology
Our lab is focused on advancing the treatment of central nervous system (CNS) cancers, particularly glioblastoma and brain metastases (GBMet). GBMet are leading causes of disability and death in Neuro-Oncology. Our research delves into the interactions between stromal cells and immune cells in the perivascular space. By understanding these interactions using a blend of clinical and preclinical experimental techniques, we aim to develop better GBMet treatments. Our lab offers a highly interdisciplinary environment. We combine cutting-edge cancer biology with big data techniques such as single-cell RNA-sequencing and spatial transcriptomics/proteomics to deeply characterize the perivascular environment. Leveraging computational approaches, including AI-assisted magnetic resonance imaging and surgical technologies, we aim to innovate new therapeutic strategies. Our work also extends to drug development, with a particular interest in targeting the perivascular space and immunosuppression, a key factor in cancer progression. Our ultimate goal is to exploit the interactions of perivascular stromal cells with the immune system to develop innovative treatments for CNS cancer patients. If you’re passionate about translational brain cancer research, our lab would like to hear from you - please include your CV and a copy of your transcripts.
Neuroimmunology
Please see previous description of research streams.
Neurosurgery
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Bioinformatics
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Cancer Biology
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Translational Oncology
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Glioblastoma
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Brain Metastasis
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Glymphatic System
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Perivascular Space
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Tumor Microenvironment
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Artificial Intelligence
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Neuroimaging
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Cancer Immunology
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Computational Biology
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Tumor Invasion
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Preclinical Models
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Interdisciplinary Research
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Supervising degrees

Neuroscience - Doctoral: Seeking Students

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