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Candice Cassia Poon, MD, PhD, FRCSC
MD obtained at the University of AlbertaPhD obtained at the University of Calgary in Neuro-Oncology and Neuroimmunology under the supervision of Dr. V. Wee Yong
FRCSC obtained after a Neurosurgical Residency at the University of Calgary
Clinical and Research Fellowship in Neurosurgical-Oncology at the University of Texas MD Anderson Texas Center (Research supervisors were Dr. Padmanee Sharma and Dr. Frederick Lang)
Areas of Research
Neuro-Oncology
Our lab is focused on advancing the treatment of central nervous system (CNS) cancers, particularly glioblastoma and brain metastases (GBMet). GBMet are leading causes of disability and death in Neuro-Oncology. Our research delves into the interactions between stromal cells and immune cells in the perivascular space. By understanding these interactions using a blend of clinical and preclinical experimental techniques, we aim to develop better GBMet treatments. Our lab offers a highly interdisciplinary environment. We combine cutting-edge cancer biology with big data techniques such as single-cell RNA-sequencing and spatial transcriptomics/proteomics to deeply characterize the perivascular environment. Leveraging computational approaches, including AI-assisted magnetic resonance imaging and surgical technologies, we aim to innovate new therapeutic strategies. Our work also extends to drug development, with a particular interest in targeting the perivascular space and immunosuppression, a key factor in cancer progression. Our ultimate goal is to exploit the interactions of perivascular stromal cells with the immune system to develop innovative treatments for CNS cancer patients. If you’re passionate about translational brain cancer research, our lab would like to hear from you.
Our lab is focused on advancing the treatment of central nervous system (CNS) cancers, particularly glioblastoma and brain metastases (GBMet). GBMet are leading causes of disability and death in Neuro-Oncology. Our research delves into the interactions between stromal cells and immune cells in the perivascular space. By understanding these interactions using a blend of clinical and preclinical experimental techniques, we aim to develop better GBMet treatments. Our lab offers a highly interdisciplinary environment. We combine cutting-edge cancer biology with big data techniques such as single-cell RNA-sequencing and spatial transcriptomics/proteomics to deeply characterize the perivascular environment. Leveraging computational approaches, including AI-assisted magnetic resonance imaging and surgical technologies, we aim to innovate new therapeutic strategies. Our work also extends to drug development, with a particular interest in targeting the perivascular space and immunosuppression, a key factor in cancer progression. Our ultimate goal is to exploit the interactions of perivascular stromal cells with the immune system to develop innovative treatments for CNS cancer patients. If you’re passionate about translational brain cancer research, our lab would like to hear from you.
Neuroimmunology
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Neurosurgery
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Bioinformatics
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Cancer Biology
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Translational Oncology
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Glioblastoma
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Brain Metastasis
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Glymphatic System
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Perivascular Space
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Tumor Microenvironment
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Artificial Intelligence
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Neuroimaging
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Cancer Immunology
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Computational Biology
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Tumor Invasion
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Preclinical Models
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Interdisciplinary Research
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Supervising degrees
Neuroscience - Doctoral: Seeking Students
Neuroscience - Masters: Seeking Students
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