Nicolas Jacquelot, MSc., PhD.

MSc in Immunology, University of Paris Saclay, Paris, France
PhD in tumor immunology, University of Paris Saclay, Paris, France

Nicolas Jacquelot

Areas of Research

Tumor immunology, immunotherapy
Our laboratory is studying the role and function of the immune system in cancer. We examine the contribution of the innate lymphoid cells (ILCs) to tumor development and therapy responses. Despite their critical role in fighting infections and promoting inflammation driving autoimmune diseases, how ILCs, considered as the innate counterpart of adaptive lymphocytes, impact tumor development, progression and cancer treatments remain vastly unknown. We leverage our expertise in mouse models, tissue biology, tumor immunology, flow-cytometry, microscopy, and multi-omics analyses to perform experiments that test the role and function of ILCs in cancer. Ongoing research efforts include (i) investigating the cellular and molecular pathways influencing ILC function in tumors, (ii) dissecting ILC signaling pathways and communication with other cells within the tumor microenvironment, and (iii) determining ILC prognostic values and therapeutic potential in cancer. Our overreaching goal is to improve cancer patient prognosis through the development of ILC-based treatments.

Supervising degrees

Immunology - Masters: Accepting Inquiries
Immunology - Doctoral: Accepting Inquiries
Biochemistry and Molecular Biology - Masters: Accepting Inquiries
Biochemistry and Molecular Biology - Doctoral: Accepting Inquiries

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