Justin MacDonald, PhD

PhD in Biology with Specialization in Biochemistry Carleton University, Ottawa, Canada

Justin MacDonald

Areas of Research

Vascular smooth muscle biology
Research activities focus on signal transduction mechanisms (i.e., zipper-interacting protein kinase & myosin phosphatase & smoothelin-like 1 protein) linked to the control of vascular smooth muscle contractility in health and disease. See- Scientific Reports (2019) 9(1):481; Microcirculation (2014) 21(3),249-58; Journal of Biological Chemistry, (2012) 287(43),36356-69; Journal of Biological Chemistry (2011) 286(42),36978-91
Chronic inflammation
Research activities explore the structure and function of the NOD-like receptor proteins in sterile inflammation See: Cell Reports (2018) 25(6):1525-1536; Journal of Clinical Investigation (2018) 128(7):2894-2913; Nature Immunology (2016) 17(10),1176-86; Nature Medicine (2012) 18(4), 600-4; Gastroenterology (2010) 139(2),542-52
Chemoproteomic drug discovery
Collaborative research employs mass spectrometry and proteomic strategies to identify therapeutic small molecules for the treatment of vascular disorders. See: Cell Chemical Biology (2018) 25(10)1195-1207; Scientific Reports (2016) 6,32118; Molecular Pharmacology (2016) 89(1),105-17; ACS Chemical Biology (2013) 8(12),2715-23

Supervising degrees

Gastrointestinal Sciences - Doctoral: Accepting Inquiries
Gastrointestinal Sciences - Masters: Accepting Inquiries
Biochemistry and Molecular Biology - Doctoral: Accepting Inquiries
Biochemistry and Molecular Biology - Masters: Accepting Inquiries
Cardiovascular and Respiratory Sciences - Doctoral: Accepting Inquiries
Cardiovascular and Respiratory Sciences - Masters: Accepting Inquiries

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