Biology of male germ line stem cells
Research in our laboratory is focused on mammalian germ line stem cell biology. Germ line stem cells (spermatogonial stem cells) form the basis of male fertility and are the only cells in an adult body that divide and can contribute genes to subsequent generations, making them immediate targets for genetic manipulation. There also appears to be considerable plasticity between germ line stem cells and pluripotent stem cells, indicating the potential to use germ line stem cells for regenerative medicine.